Material Safety Data Sheet for 1-Bromoheptane

Identification

Product Name: 1-Bromoheptane
Synonyms: Heptane, 1-bromo-; n-Heptyl bromide
Chemical Formula: C7H15Br
CAS Number: 629-04-9
Manufacturer: Refer to supplier details on shipment label
Intended Use: Laboratory chemical, organic synthesis intermediate

Hazard Identification

GHS Classification: Flammable Liquids (Category 3), Skin Irritation (Category 2), Eye Irritation (Category 2A), Acute Toxicity – Oral and Inhalation (Category 4), Specific Target Organ Toxicity - Single Exposure (Category 3)
Label Elements: Exclamation Mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, harmful if swallowed
Precautionary Statements: Avoid breathing vapors, wear protective gloves and eye protection, wash skin thoroughly after handling, store in well-ventilated place

Composition / Information on Ingredients

Chemical Name: 1-Bromoheptane
Concentration: 98-100%
Impurities: Trace brominated heptanes
Molecular Weight: 179.10 g/mol
EC Number: 211-070-7

First Aid Measures

Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms appear
Skin Contact: Remove contaminated clothing, rinse skin with soap and water, consult a healthcare professional for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, get medical advice if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, call poison control center or physician immediately
Most Important Symptoms: Burning sensation, coughing, respiratory discomfort, redness and pain at exposed sites

Fire-Fighting Measures

Extinguishing Media: Use foam, dry chemical, carbon dioxide, do not use water jet
Special Hazards: Emits toxic fumes of hydrogen bromide and carbon oxides upon combustion
Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective gear
Advice: Evacuate area, stay upwind, cool exposed containers with water spray to prevent bursting
Flammability: Combustible liquid with moderate fire hazard

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, splash goggles, suitable protective clothing, use respiratory protection if vapor concentration is high
Environmental Precautions: Prevent entry into waterways, soil, and drainage systems
Methods for Containment: Stop leak if safe to do so, contain spillage using sand, earth, or inert absorbent material
Cleanup Procedures: Place collected material in properly labeled receptacles, ventilate area, wash spill site with detergent and water after pickup

Handling and Storage

Safe Handling: Use in well-ventilated areas, avoid inhaling vapors, prevent contact with skin and eyes, handle away from sources of ignition, use spark-proof tools
Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated location away from heat, open flames, and oxidizing agents
Incompatibilities: Avoid contact with strong oxidizers, acids, alkali metals, and reducing agents
Specific Storage Requirements: Ground/bond container and receiving equipment, protect against physical damage

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits established
Engineering Controls: Use chemical fume hood or local exhaust ventilation to keep airborne concentrations below exposure guidelines
Hand Protection: Wear nitrile or neoprene gloves
Skin Protection: Wear long-sleeved clothing and safety shoes
Eye Protection: Safety goggles or face shield
Respiratory Protection: In case of inadequate ventilation, wear appropriate NIOSH-approved respirator
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke during use, remove contaminated clothing before entering eating areas

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Slight, characteristic
Boiling Point: 190–195°C
Melting Point: -65°C
Density: 1.14 g/cm³ at 20°C
Solubility: Immiscible in water, soluble in ethanol, ether, and most organic solvents
Vapor Pressure: 0.12 mmHg at 25°C
Flash Point: 66°C (closed cup)
Evaporation Rate: Not rapid
Viscosity: 3.1 mPa.s at 25°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not highly reactive under normal laboratory conditions
Possibility of Hazardous Reactions: May form hazardous decomposition products upon combustion or contact with strong oxidizers
Conditions to Avoid: Heat, flame, sparks, incompatibles
Incompatible Materials: Strong oxidizers, acids, alkali metals
Hazardous Decomposition Products: Bromine, hydrogen bromide, oxides of carbon

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin
LD50 (Oral, Rat): >2000 mg/kg (estimate)
LD50 (Dermal, Rabbit): Data not fully established, but expected to be above 2000 mg/kg
Symptoms of Exposure: Coughing, sore throat, irritation to skin and eyes, drowsiness, headache, nausea
Chronic Toxicity: Long-term exposure may cause liver or kidney damage
Carcinogenicity: Not classified as a carcinogen based on available data
Reproductive Toxicity: No evidence of reproductive harm in animal studies
Sensitization: No data showing allergic skin reaction or respiratory sensitization

Ecological Information

Ecotoxicity: Toxic to aquatic organisms, may cause long-lasting harmful effects in aquatic environments
Persistence and Degradability: Not readily biodegradable, potentially persistent in environment
Bioaccumulative Potential: Expected to have moderate bioaccumulation in aquatic organisms
Mobility in Soil: Low water solubility limits significant migration through soil
Other Adverse Effects: Avoid release to natural waters and sewage systems

Disposal Considerations

Waste from Residues: Dispose of via authorized chemical waste disposal contractor in accordance with local, regional, and national environmental regulations
Contaminated Packaging: Clean empty containers before disposal or recycling, puncture and triple rinse
Special Instructions: Do not discharge waste into drains, dispose as hazardous chemical waste, ensure complete combustion or safe chemical destruction in an approved incinerator

Transport Information

UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains 1-bromoheptane)
Transport Hazard Class: 3
Packing Group: III
Marine Pollutant: Yes
Environmental Hazards: Classified as hazardous for aquatic environment
Transport Precautions: Avoid transport with foodstuffs and animal feed, handle with care to prevent leaks and spills, keep away from incompatible materials during shipment

Regulatory Information

TSCA Status: Listed on the United States TSCA Inventory
REACH Status: Subject to registration under Regulation (EC) No. 1907/2006
OSHA Status: Listed as hazardous under OSHA Hazard Communication Standard
WHMIS Classification (Canada): Class B2 (Flammable liquid), D2B (Toxic material causing other toxic effects)
Other Regulations: Subject to SARA Title III reporting, not listed under California Proposition 65
Labeling Requirements: Ensure product received and handled according to glob​ally harmonized standards, training required for safe use
Additional Local Requirements: Consult specific country and state regulations for worker protection and environmental control